Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12669697 | 0.74 | SMN1; SMN2 (0.53) | ATMKMT2ALMNAALDH1A1GAA | |
| SCHEMBL28283505 | 0.63 | CTSB (0.47) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL8358228 | 0.61 | CTSB (0.49) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL12166130 | 0.60 | CHRM2 (0.43) | — | |
| SCHEMBL1523605 | 0.59 | MIF (0.45) | ATMKMT2AMEN1LMNAC5AR1 | |
| SCHEMBL17141352 | 0.59 | CTSB (0.36) | — | |
| SCHEMBL13440548 | 0.58 | HPGD (0.56) | ATMKMT2AMEN1HPGDLMNA | |
| SCHEMBL5957522 | 0.58 | HPGD (0.49) | ATMKMT2AMEN1HPGDC5AR1 | |
| SCHEMBL24452836 | 0.57 | CTSB (0.40) | — | |
| SCHEMBL15164280 | 0.57 | TP53 (0.64) | HPGDC5AR1ALDH1A1GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060036-A1 | BICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |