Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.80 |
| ▸ | TGM2 | P21980 | 1/20 | 0.74 |
| ▸ | HINT1 | P49773 | 1/20 | 0.69 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.68 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.68 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.68 |
| ▸ | KRAS | P01116 | 9/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.65 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.65 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238744 | 1.00 | NT5E (0.80) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL14201234 | 0.94 | TGM2 (0.81) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL15702883 | 0.94 | TGM2 (0.81) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL26067577 | 0.93 | NT5E (0.70) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| E626 SCHEMBL18759049 | 0.92 | NT5E (0.83) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| E626 SCHEMBL21803790 | 0.92 | NT5E (0.83) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| E626 SCHEMBL13497991 | 0.92 | NT5E (0.83) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| E626 SCHEMBL20677331 | 0.92 | NT5E (0.83) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| E626 SCHEMBL21163348 | 0.92 | NT5E (0.83) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| E626 SCHEMBL18763818 | 0.92 | NT5E (0.83) | NT5ETGM2HINT1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935814-B2 | Nitroguanosine-3′ 5′-cyclic monophosphate compound and protein kinase G activating agent | KUMAMOTO UNIVERSITY (JP) | 2011-05-03 | — | — | US | disclosed |