Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.49 |
| ▸ | CTSS | P25774 | 8/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804956 | 0.90 | CTSK (0.50) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL28804957 | 0.90 | CTSK (0.50) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13621256 | 0.88 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL6168773 | 0.88 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL19000135 | 0.88 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL1318454 | 0.88 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL6168769 | 0.88 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL21675512 | 0.88 | CTSK (0.61) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL23332856 | 0.85 | CTSS (0.40) | CTSKCTSSCTSLCTSBCA1 | |
| Hydrochloric Acid SCHEMBL26645727 | 0.83 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322171-A2 | Fluorine labeled L-glutamic acid derivatives | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |