Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293190 | 0.92 | CTSK (0.49) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL7954021 | 0.90 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL20745305 | 0.90 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL7066210 | 0.90 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL18560556 | 0.90 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL1319454 | 0.90 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL13263380 | 0.90 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL12673233 | 0.90 | CTSK (0.49) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL28804957 | 0.87 | CTSK (0.50) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL17559 | 0.85 | CTSL (0.66) | CTSKCTSSCTSLCTSBFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102206247-B | Novel peptides as NS3/NS4a serine protease inhibitors of hepatitis C virus | DENDREON CORP | 2013-03-27 | — | — | CN | disclosed |