SCHEMBL12674281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12666733	0.83	CHEK1 (0.69)	CHEK1ACHEMAPT
	SCHEMBL12666721	0.81	CHEK1 (0.56)	CHEK1ACHEGABRPGABRDGABRA1
	SCHEMBL12666260	0.80	CHEK1 (0.66)	CHEK1ACHE
	SCHEMBL1428187	0.78	CHEK1 (1.00)	CHEK1ACHEALK
	SCHEMBL12666705	0.77	MAPT (0.64)	CHEK1ACHEALKMAPT
	SCHEMBL9284633	0.75	ALK (0.56)	ALK
	SCHEMBL13572850	0.73	ALK (0.43)	CHEK1ACHEALKMAPTMAP4K4
	SCHEMBL1427647	0.72	CHEK1 (0.58)	CHEK1ACHEGABRPGABRDGABRA1
	SCHEMBL2108962	0.72	CCNC (0.56)	CHEK1MAPTMAP4K4KDM4EALDH1A1
	SCHEMBL1427592	0.72	CHEK1 (0.56)	CHEK1ACHEALKMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.