Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.64 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 3/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497919 | 1.00 | TDP1 (0.67) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL16602989 | 0.96 | TDP1 (0.68) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL16715735 | 0.96 | TDP1 (0.68) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL19775860 | 0.93 | TDP1 (0.69) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL21101323 | 0.93 | TDP1 (0.69) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL19775861 | 0.93 | TDP1 (0.69) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL19776155 | 0.93 | TDP1 (0.69) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL12836947 | 0.93 | TDP1 (0.69) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL18779801 | 0.91 | TDP1 (0.78) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL15672766 | 0.91 | F2 (0.66) | TDP1PLCD1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117569-A1 | POLYMIDE NUCLEIC ACID DERIVATIVES, AND AGENTS AND PROCESSES FOR PREPARING THEM | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
| US-7897346-B2 | Polyamide nucleic acid derivatives and agents, and processes for preparing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-03-01 | — | — | US | disclosed |
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | ROCHE DIAGNOSTICS GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | ROCHE DIAGNOSTICS GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100022016-A1 | POLYAMIDE NUCLEIC ACID DERIVATIVES AND AGENTS, AND PROCESSES FOR PREPARING THEM | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-01-28 | — | — | US | disclosed |
| US-7550582-B2 | labeled Peptide Nucleic Acid (PNA) derivatives which carry one or more phosphoryl radicals at the N terminus of the PNA backbone for fluorescence in-situ hybridization (FISH) detection; can be purified using chromatography or electrophoresis; use as pharmaceuticals and diagnostic agents | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-06-23 | — | — | US | disclosed |
| US-20080070258-A1 | labeled Peptide Nucleic Acid (PNA) derivatives which carry one or more phosphoryl radicals at the N terminus of the PNA backbone for fluorescence in-situ hybridization (FISH) detection; can be purified using chromatography or electrophoresis; use as pharmaceuticals and diagnostic agents | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-7241882-B2 | Polyamide nucleic acid derivatives, and agents, and processes for preparing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070258-A1 | labeled Peptide Nucleic Acid (PNA) derivatives which carry one or more phosphoryl radicals at the N terminus of the PNA backbone for fluorescence in-situ hybridization (FISH) detection; can be purified using chromatography or electrophoresis; use as pharmaceuticals and diagnostic agents | NPPA, PNKP, PHAX | TDP1 109/4885PLCD1 217/4885F2 2623/4885 |
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | POLM, IGF2BP1, POLRMT | TDP1 319/4885PLCD1 3702/4885F2 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.