Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 5/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.55 |
| ▸ | ITGAL | P20701 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428900 | 0.83 | ALOX15 (0.58) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL27916352 | 0.82 | ALOX15 (0.62) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL19737124 | 0.81 | ACE (0.70) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL1263833 | 0.81 | KDM4E (0.72) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL1263822 | 0.81 | KDM4E (0.72) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL16750046 | 0.81 | ACE (0.70) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL28982976 | 0.81 | ALOX15 (0.64) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL15592745 | 0.81 | ACE (0.70) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL30782236 | 0.81 | ALOX15 (0.70) | ACEALOX15SMN1; SMN2ECE1ITGB2 | |
| SCHEMBL8254531 | 0.80 | ACE (0.68) | ACEALOX15SMN1; SMN2ECE1ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089529-B1 | PRODUCTION OF STEREOISOMERS OF MONATIN VIA D-TRYPTOPHAN | CARGILL INC (US) | 2019-03-20 | — | — | EP | disclosed |
| US-9719079-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2017-08-01 | — | — | US | disclosed |
| EP-3168299-A2 | POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF STEREOISOMERS OF MONATIN AND THEIR PRECURSORS | Cargill, Incorporated (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-3153580-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BASF Enzymes LLC (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9518280-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | CARGILL, INCORPORATED (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2385108-B1 | Aldolases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160251643-A1 | Aldolases, Nucleic Acids Encoding Them and Methods for Making and Using Them | VERENIUM CORPORATION | 2016-09-01 | — | — | US | disclosed |
| EP-2354240-B1 | Polypeptides and biosynthetic pathways | CARGILL INC (US) | 2016-07-06 | — | — | EP | disclosed |
| EP-2361976-B1 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors | CARGILL INC (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9290755-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-03-22 | — | — | US | disclosed |
| US-20050170041-A1 | Chewing gum compositions comprising monatin and methods for making same | CARGILL, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050112260-A1 | Monatin tabletop sweetener compositions and methods of making same | CARGILL, INC. | 2005-05-26 | — | — | US | disclosed |
| US-20050106305-A1 | Beverage compositions comprising monatin and methods of making same | CARGILL, INC. | 2005-05-19 | — | — | US | disclosed |
| WO-2005042756-A2 | PRODUCTION OF MONATIN AND MONATIN PRECURSORS | CARGILL, INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2005020721-A1 | BEVERAGE COMPOSITIONS COMPRISING MONATIN AND METHODS OF MAKING SAME | CARGILL, INCORPORATED (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-2005016022-A1 | CHEWING GUM COMPOSITIONS COMPRISING MONATIN AND METHODS OF MAKING SAME | CARGILL, INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005014839-A2 | MONATIN TABLETOP SWEETENER COMPOSITIONS AND METHODS OF MAKING SAME | CARGILL, INCORPORATED (US) | 2005-02-17 | — | — | WO | disclosed |
| EP-1503985-A2 | POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS | Cargill, Incorporated (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20040063175-A1 | Polypeptides and biosynthetic pathways | CARGILL, INCORPORATED | 2004-04-01 | — | — | US | disclosed |
| WO-2003091396-A2 | POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS | CARGILL, INCORPORATED (US) | 2003-11-06 | — | — | WO | disclosed |