Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801336 | 0.86 | ALDH1A1 (0.54) | KDM4EGAAHTTACHEHTR4 | |
| SCHEMBL2596444 | 0.84 | GAA (0.66) | KDM4EGAAHTTACHEHTR4 | |
| SCHEMBL1219388 | 0.83 | CYP3A4 (0.50) | HTTACHECA9ALDH1A1CYP3A4 | |
| SCHEMBL24106157 | 0.80 | HTT (0.61) | KDM4EGAAHTTACHECA9 | |
| SCHEMBL6371675 | 0.79 | CYP3A4 (0.55) | KDM4EGAAHTTCA9ALDH1A1 | |
| SCHEMBL16400171 | 0.79 | HTR4 (0.48) | KDM4EGAAACHEHTR4ALDH1A1 | |
| SCHEMBL7351910 | 0.79 | GAA (0.73) | GAAHTR4ALDH1A1CYP3A4LMNA | |
| SCHEMBL20630769 | 0.78 | HTT (0.68) | KDM4EHTTCA9ALDH1A1CYP3A4 | |
| SCHEMBL23015575 | 0.78 | HTR4 (0.55) | KDM4EGAAACHEHTR4ALDH1A1 | |
| SCHEMBL24106211 | 0.77 | TNFSF11 (0.51) | HTTCA9CYP3A4LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316469-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |