Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.55 |
| ▸ | HTR1A | P08908 | 6/20 | 0.55 |
| ▸ | HTR7 | P34969 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR2B | P41595 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680657 | 0.88 | ALDH1A1 (0.58) | DRD3HTR1AHTR7TDP1HTR2B | |
| SCHEMBL30296953 | 0.81 | ALDH1A1 (0.64) | DRD3HTR1AHTR7TDP1HTR2A | |
| SCHEMBL155413 | 0.81 | ALDH1A1 (0.64) | DRD3HTR1AHTR7TDP1HTR2A | |
| SCHEMBL29144139 | 0.81 | HDAC3 (0.56) | DRD3HTR1AHTR7HTR2AHTR2B | |
| SCHEMBL589583 | 0.80 | ALDH1A1 (0.72) | DRD3HTR1AHTR7TDP1HTR2A | |
| SCHEMBL6097277 | 0.80 | HTR7 (0.59) | DRD3HTR1AHTR7HTR2AHTR2B | |
| SCHEMBL12680647 | 0.80 | KDM4E (0.57) | DRD3HTR1AHTR7HTR2AHTR2B | |
| SCHEMBL23001347 | 0.79 | ALDH1A1 (0.75) | DRD3HTR1AHTR7HTR2AHTR2B | |
| SCHEMBL11038187 | 0.79 | ALDH1A1 (0.75) | DRD3HTR1AHTR7HTR2AHTR2B | |
| SCHEMBL910697 | 0.79 | ALDH1A1 (0.75) | DRD3HTR1AHTR7HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273772-B2 | Heteroaryl compounds as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-25 | — | — | US | disclosed |