Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 5/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23001347 | 0.98 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL11038187 | 0.98 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL910697 | 0.98 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL8429723 | 0.98 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL14393531 | 0.98 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL30296953 | 0.95 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL155413 | 0.95 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL21142468 | 0.89 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL13487187 | 0.87 | MAOA (0.59) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 | |
| SCHEMBL3246920 | 0.87 | MAOA (0.59) | ALDH1A1CYP1A2CYP2D6CYP2C19HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874105-B | Preparation method of visible light and water promoted homoallylic amine compound | 大连理工大学 | 2023-03-03 | — | — | CN | claimed |
| CN-114874105-A | Preparation method of visible light and water promoted homoallylic amine compound | 大连理工大学 | 2022-08-09 | — | — | CN | claimed |
| EP-0245960-B1 | PROCESS FOR PREPARING N-ACYLTETRAHYDROISOQUINOLINE | Takasago Perfumery Co., Ltd. (JP) | 1992-07-29 | — | — | EP | claimed |
| CN-110891938-B | Tetrahydro-benzo [ D ] azepine derivatives as GPR120 modulators | 卡尔丹治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-20230150998-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns, Inc. | 2023-05-18 | — | — | US | disclosed |
| CN-115772169-A | Indoline [2,1-a ] isoquinoline derivative, preparation method and application | 郑州大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-114874105-B | Preparation method of visible light and water promoted homoallylic amine compound | 大连理工大学 | 2023-03-03 | — | — | CN | disclosed |
| US-11084777-B2 | Method for preparing alkylamines | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2021-08-10 | — | — | US | disclosed |
| CN-110891938-A | Tetrahydro-benzo [ D ] azepin slow derivatives as GPR120 modulators | 卡尔丹治疗有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-20190084917-A1 | Method for Preparting Alkylamines | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2019-03-21 | — | — | US | disclosed |
| CN-108084179-A | A kind of compound with spirane structure, its preparation method and application | 上海医药工业研究院 | 2018-05-29 | — | — | CN | disclosed |
| US-5124337-A | Treating atherosclerosis | SCHERING CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| US-5124337-A | Treating atherosclerosis | SCHERING CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0245960-A2 | Process for preparing N-acyltetrahydroisoquinoline | Takasago Perfumery Co., Ltd. (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0245960-A2 | Process for preparing N-acyltetrahydroisoquinoline | Takasago Perfumery Co., Ltd. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4013666-A | (8α,13Aβ)-8-CARBOCYCLIC/CARBOCYCLIC METHYL-5,8,13,13A-TETRAHYDRO-2,3,10,11-TETRAMETHOXY-6H-dibenzo[a,g]quinolizines and intermediates thereto | G. D. SEARLE & CO. (US) | 1977-03-22 | — | — | US | disclosed |
| US-4013644-A | [8 α(E), 13aβ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2-phenylethenyl)-6H-dibenzo[a,g]quinolizines and intermediates thereto | G. D. SEARLE & CO. (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084777-B2 | Method for preparing alkylamines | ALKBH2, ACR, ALKBH1 | ALDH1A1 880/4885CYP1A2 146/4885CYP2D6 382/4885 |
| US-20190084917-A1 | Method for Preparting Alkylamines | ALKBH2, ACR, ALKBH5 | ALDH1A1 827/4885CYP1A2 122/4885CYP2D6 367/4885 |
| US-20230150998-A1 | COMPOUNDS AS GLP-1R AGONISTS | GLP1R, GIPR, GCGR | ALDH1A1 3182/4885CYP1A2 4109/4885CYP2D6 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.