Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17724375 | 1.00 | SCN4A (0.41) | SCN4AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL19305438 | 1.00 | SCN4A (0.41) | SCN4AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL12495465 | 0.81 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL4618228 | 0.74 | SLC6A2 (0.45) | OPRM1GRIN2B | |
| SCHEMBL4625904 | 0.73 | MME (0.36) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL10418527 | 0.72 | CYP2C19 (0.42) | — | |
| SCHEMBL535200 | 0.72 | CYP2D6 (0.38) | SCN4A | |
| SCHEMBL5695495 | 0.69 | USP19 (0.38) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL101140 | 0.69 | DPP4 (0.50) | SCN4ADPP4F2GRIN2DGRIN3B | |
| SCHEMBL30559582 | 0.69 | DPP4 (0.50) | SCN4ADPP4F2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683704-B1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI SA (FR) | 2014-12-17 | — | — | EP | disclosed |
| US-8828995-B2 | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof | SANOFI (FR) | 2014-09-09 | — | — | US | disclosed |
| US-8828995-B2 | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof | SANOFI (FR) | 2014-09-09 | — | — | US | disclosed |
| WO-2012120053-A1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |