Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16181498 | 0.83 | ABCG2 (0.67) | KDM1AABCG2ABCB1TNFRSF1APTPN1 | |
| SCHEMBL16181212 | 0.74 | ABCG2 (0.59) | KDM1AABCG2ABCB1TNFRSF1APTPN1 | |
| SCHEMBL30928257 | 0.73 | NFE2L2 (0.71) | KDM1AABCG2PRKDCTNFRSF1ACYP1A2 | |
| SCHEMBL13567360 | 0.73 | PDE4A (0.64) | ABCG2TNFRSF1APDE4APDE4BPDE4C | |
| SCHEMBL14021812 | 0.73 | PDE4A (0.47) | ABCG2ABCB1TNFRSF1APDE4APDE4B | |
| SCHEMBL2338997 | 0.72 | PRKDC (0.58) | KDM1AABCG2PRKDCCA12CA1 | |
| SCHEMBL2338994 | 0.72 | PRKDC (0.58) | KDM1AABCG2PRKDCCA12CA1 | |
| SCHEMBL10674510 | 0.72 | TSHR (0.58) | ABCG2ABCB1TNFRSF1APDE4APDE4B | |
| SCHEMBL20244284 | 0.71 | ABCG2 (0.55) | ABCG2ABCB1TNFRSF1APDE4APDE4B | |
| SCHEMBL24254433 | 0.69 | CA12 (0.53) | ABCG2TNFRSF1APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012118935-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PROTEOTECH INC (US) | 2012-09-07 | — | — | WO | disclosed |