Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582957 | 0.84 | ABCG2 (0.79) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL10582964 | 0.84 | ABCG2 (0.79) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL13567360 | 0.78 | PDE4A (0.64) | ABCG2TNFRSF1AMEN1KMT2APDE4A | |
| SCHEMBL4995196 | 0.76 | TUBB4A (0.58) | ABCG2PDE4BABCB1SMN1; SMN2 | |
| SCHEMBL4995193 | 0.76 | TUBB4A (0.58) | ABCG2PDE4BABCB1SMN1; SMN2 | |
| SCHEMBL20244293 | 0.75 | MAPT (0.69) | TNFRSF1AKMT2ALMNAMAPTATM | |
| SCHEMBL15807424 | 0.74 | ABCG2 (0.63) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL14306013 | 0.74 | ABCG2 (0.79) | ABCG2TNFRSF1ALMNAMAPTABCB1 | |
| SCHEMBL23395752 | 0.72 | HDAC2 (0.51) | LMNAMAPTP4HBKDM4EALDH1A1 | |
| SCHEMBL25221520 | 0.72 | P4HB (0.73) | ABCG2TNFRSF1AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333153-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) | 2018-06-13 | — | — | EP | disclosed |