Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | CSK | P41240 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263082 | 0.83 | PDE4A (0.90) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL27772535 | 0.80 | CYP1A1 (0.71) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL20244284 | 0.78 | ABCG2 (0.55) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL28261930 | 0.78 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL28161502 | 0.76 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL2791897 | 0.75 | MAOA (0.64) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL12810895 | 0.75 | TUBB1 (0.59) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL2791904 | 0.75 | MAOA (0.64) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL28035920 | 0.74 | MAOA (0.63) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL12682383 | 0.73 | KDM1A (0.51) | PDE4APDE4BPDE4CPDE4DABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146910-A1 | 4, 6-DIPHENYLPYRID-2-0NES AGAINST CANCER | SPEAR THERAPEUTICS LIMITED DE MONTFORT UNIVERSITY (GB) | 2009-12-10 | — | — | WO | disclosed |