Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269516 | 0.88 | GRM2 (0.67) | GRM2 | |
| SCHEMBL1269318 | 0.83 | GRM2 (0.51) | GRM2 | |
| SCHEMBL1269301 | 0.81 | GRM2 (0.71) | GRM2 | |
| SCHEMBL1268405 | 0.77 | HTR6 (0.55) | GRM2 | |
| SCHEMBL1268394 | 0.75 | RAB9A (0.43) | GRM2 | |
| SCHEMBL2823359 | 0.71 | GRM2 (0.66) | GRM2 | |
| SCHEMBL9844322 | 0.70 | GRM2 (0.69) | GRM2 | |
| SCHEMBL8008418 | 0.70 | GRM2 (0.61) | GRM2 | |
| SCHEMBL11740299 | 0.69 | GRM2 (1.00) | GRM2 | |
| SCHEMBL1269334 | 0.68 | FADS1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | GRM2 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.