Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372103 | 0.91 | CNR1 (0.34) | KMT2AMALT1PIK3CACNR1CNR2 | |
| SCHEMBL12682965 | 0.90 | KMT2A (0.39) | KMT2ABACE1USP30CSF1RMEN1 | |
| SCHEMBL12683237 | 0.86 | BACE1 (0.33) | KMT2ABACE1USP30TBK1 | |
| SCHEMBL15372101 | 0.80 | HCRTR1 (0.36) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL12683233 | 0.80 | MALT1 (0.32) | KMT2AMALT1PIK3CAUSP30SMN1; SMN2 | |
| SCHEMBL15372099 | 0.77 | TBK1 (0.30) | TBK1 | |
| SCHEMBL12683010 | 0.77 | PREP (0.39) | — | |
| SCHEMBL15372104 | 0.75 | CNR1 (0.33) | MALT1PIK3CACNR1CNR2PIK3R1 | |
| SCHEMBL12682980 | 0.72 | ALDH1A1 (0.36) | KMT2ATBK1MEN1ALDH1A1TSHR | |
| SCHEMBL15372079 | 0.72 | NR1I2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |