Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372100 | 0.91 | — | — | |
| SCHEMBL12683233 | 0.86 | MALT1 (0.32) | USP30 | |
| SCHEMBL12683237 | 0.80 | BACE1 (0.33) | USP30HSD17B10 | |
| SCHEMBL15372102 | 0.79 | HCRTR1 (0.37) | USP30 | |
| SCHEMBL15372104 | 0.78 | CNR1 (0.33) | — | |
| SCHEMBL15372099 | 0.75 | TBK1 (0.30) | HSD17B10 | |
| SCHEMBL12683161 | 0.74 | KMT2A (0.38) | USP30 | |
| SCHEMBL12683099 | 0.74 | PREP (0.39) | — | |
| SCHEMBL12683101 | 0.73 | AAK1 (0.35) | — | |
| SCHEMBL12682979 | 0.73 | AAK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |