SCHEMBL1268486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Acetic Acid SCHEMBL28282467	0.92	POLB (0.49)	POLBFLT1FLT4KDRSLC1A3
	SCHEMBL9846425	0.85	POLB (0.54)	POLBFLT1FLT4KDRSLC1A3
	SCHEMBL29543742	0.84	POLB (0.56)	POLBFLT1FLT4KDRSLC1A3
	SCHEMBL2351670	0.84	POLB (0.56)	POLBFLT1FLT4KDRSLC1A3
	SCHEMBL20528790	0.80	CA9 (0.50)	GAACA12CA1CA2CA9
	SCHEMBL1269864	0.79	FLT1 (0.49)	FLT1FLT4KDRTSHREDNRA
	SCHEMBL27567092	0.79	CA1 (0.50)	POLBSLC1A3SLC1A2SLC1A1ALDH1A1
	SCHEMBL10784100	0.78	POLB (0.58)	POLBFLT1FLT4KDRSLC1A3
	SCHEMBL3954909	0.78	POLB (0.58)	POLBFLT1FLT4KDRSLC1A3
	SCHEMBL8560217	0.77	CSNK1A1 (0.41)	ALDH1A1L3MBTL1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.