Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264558 | 0.85 | BRS3 (0.39) | CSNK1A1CSNK1DCSNK1ECSNK1G2CSNK1G1 | |
| SCHEMBL1268486 | 0.77 | POLB (0.51) | CA12CA2CA9CA1ALDH1A1 | |
| SCHEMBL8555843 | 0.75 | CA1 (0.32) | CA12CA2CA9CA14CA1 | |
| SCHEMBL8212413 | 0.75 | LMNA (0.49) | CSNK1A1CSNK1DCSNK1ECSNK1G2CSNK1G1 | |
| SCHEMBL8323021 | 0.72 | ALDH1A1 (0.47) | CSNK1A1CSNK1DCSNK1ECSNK1G2CSNK1G1 | |
| SCHEMBL2879049 | 0.72 | NAPRT (0.44) | CSNK1A1CSNK1DCSNK1ECSNK1G2CSNK1G1 | |
| SCHEMBL51312 | 0.72 | CA12 (0.58) | LMNACA12CA2CA9CA14 | |
| SCHEMBL13971307 | 0.71 | CSNK1A1 (0.46) | CSNK1A1CSNK1DCSNK1ECSNK1G2CSNK1G1 | |
| SCHEMBL8560220 | 0.71 | F2 (0.47) | LMNACA12CA2CA9CA14 | |
| SCHEMBL7908992 | 0.71 | GSTO1 (0.45) | CSNK1A1CSNK1DCSNK1ECSNK1G2CSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618209-B1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-12-23 | — | — | EP | disclosed |
| US-5459138-A | Dysfunctions of glutamatergic neurotransmission associated with learning and memory | ADIR ET COMPAGNIE (FR) | 1995-10-17 | — | — | US | disclosed |
| EP-0618209-A1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |