⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376 | 0.76 | — | — | |
| SCHEMBL6570936 | 0.76 | MEN1 (0.32) | — | |
| SCHEMBL6573282 | 0.72 | — | — | |
| SCHEMBL514497 | 0.72 | — | — | |
| SCHEMBL225859 | 0.72 | — | — | |
| SCHEMBL5534960 | 0.70 | CYP3A4 (0.33) | — | |
| SCHEMBL8746605 | 0.70 | CA2 (0.38) | — | |
| SCHEMBL5393746 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL2347179 | 0.70 | CA2 (0.38) | — | |
| SCHEMBL5478792 | 0.70 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120044-A1 | MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS | QIAGEN GMBH (DE) | 2010-05-13 | — | — | US | claimed |
| EP-1196631-B1 | Modifications of ribonucleic acids | CYCLOPS GENOME SCIENCES LTD (GB) | 2006-12-06 | — | — | EP | claimed |
| US-20050272679-A1 | Modified polynucleotides and uses thereof | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2005-12-08 | — | — | US | claimed |
| US-20030039985-A1 | Modified polynucleotides and uses thereof | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2003-02-27 | — | — | US | claimed |
| EP-1196631-A1 | POLYNUCLEOTIDES | Cyclops Genome Sciences Limited (GB) | 2002-04-17 | — | — | EP | claimed |
| WO-2001094626-A1 | POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2001-12-13 | — | — | WO | claimed |
| US-5633231-A | CYTOMEGALOVIRUS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | claimed |
| US-5475016-A | Hypotensive, anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | claimed |
| US-5420149-A | Hypotensive agents and artheriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | claimed |
| US-5376671-A | Cardiovascular disorders, hypotensive agents, anticholesterol agent | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-27 | — | — | US | claimed |
| US-5352687-A | Hypotensive agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-04 | — | — | US | claimed |
| US-5276024-A | 3-substituted cephalosporins, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| EP-0229381-B1 | METHIONINE-SUBSTITUTED 1,4-DIHYDROPYRIDINES, PROCESS FOR THE PREPARATION AND THEIR USE | BAYER AG (DE) | 1990-05-30 | — | — | EP | claimed |
| US-4841042-A | Process for the preparation of carbapenem intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| US-4840946-A | Benzazolythio-carbapenem antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| US-4808622-A | ANTIHYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
| EP-0268963-A1 | Benzazolylthio-carbapenem antibiotics | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0195963-A1 | Process for the preparation of carbapenem intermediates | BAYER AG (DE) | 1986-10-01 | — | — | EP | claimed |
| CN-112574116-B | Method for preparing glufosinate intermediate and analogue | 利尔化学股份有限公司 | 2022-08-23 | — | — | CN | disclosed |
| EP-0195963-A1 | Process for the preparation of carbapenem intermediates | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |