Sugi Predict

Sugi Predict / Compounds / SCHEMBL1268558

SCHEMBL1268558

SCHEMBL1268558

CCNCCCCN(C)C

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 3/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ MEN1 O00255 1/20 0.52
▸ GLA P06280 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ TSHR P16473 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ DNM1 Q05193 3/20 0.48
▸ KDM1A O60341 5/20 0.46
▸ PAOX Q6QHF9 1/20 0.45
▸ CYP2C9 P11712 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.41
▸ SAT1 P21673 1/20 0.39
▸ PRMT3 O60678 1/20 0.38
▸ CARM1 Q86X55 1/20 0.38
▸ PRMT6 Q96LA8 1/20 0.38
▸ PRMT1 Q99873 1/20 0.38
▸ PRMT8 Q9NR22 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15966125 0.97 TSHR (0.55) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL15966140 0.97 TSHR (0.55) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL15966144 0.97 TSHR (0.55) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL15966128 0.97 TSHR (0.55) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL14044481 0.97 TSHR (0.55) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL1268746 0.92 — —
Hydrochloric Acid SCHEMBL3589381 0.90 TDP1 (0.56) CYP2C19CYP1A2MEN1GLAKMT2A
Hydrochloric Acid SCHEMBL3184204 0.90 TDP1 (0.56) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL756103 0.86 TDP1 (0.64) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL6747424 0.83 ALDH1A1 (0.65) CYP2C19CYP1A2MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634265-A1 POLYESTERS CLARIANT INTERNATIONAL LTD (CH) 2025-10-22 — — EP disclosed
WO-2024126303-A1 POLYESTERS CLARIANT INTERNATIONAL LTD (CH) 2024-06-20 — — WO disclosed
WO-2021026109-A1 DEGRADERS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2021-02-11 — — WO disclosed
WO-2019173082-A1 SUBSTITUTED L,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES Zeno Royalties & Milestones, LLC (US) 2019-09-12 — — WO disclosed
WO-2018089695-A1 TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USE DYNAVAX TECHNOLOGIES CORPORATION (US) 2018-05-17 — — WO disclosed
EP-2310396-B1 MACROCYCLIC INDOLE DERIVATIVES USEFUL AS HEPATITIS C VIRUS INHIBITORS JANSSEN SCIENCES IRELAND UC (IE) 2017-09-06 — — EP disclosed
EP-2927228-B1 Novel physiologically active substances EISAI R&D MAN CO LTD (JP) 2016-09-07 — — EP disclosed
US-20160039834-A1 CARM1 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2016-02-11 — — US disclosed
EP-2927228-A1 Novel physiologically active substances Eisai R&D Management Co., Ltd. (JP) 2015-10-07 — — EP disclosed
EP-2266978-B1 Novel physiologically active substances EISAI R&D MAN CO LTD (JP) 2015-05-20 — — EP disclosed
US-20080275059-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES KOTAKE YOSHIHIKO 2008-11-06 — — US disclosed
US-20080255146-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES MICROBIOPHARM JAPAN CO., LTD. (JP) 2008-10-16 — — US disclosed
US-7256178-B2 Physiologically active substances EISAI CO., LTD. (JP) 2007-08-14 — — US disclosed
US-20060241171-A1 Novel physiologically active substances MICROBIOPHARM JAPAN CO., LTD. (JP) 2006-10-26 — — US disclosed
US-20060235002-A1 Novel physiologically active substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2006-10-19 — — US disclosed
US-20060009439-A1 Novel physiologically active substances MERCIAN CORPORATION (JP) 2006-01-12 — — US disclosed
US-20050245514-A1 Novel physiologically active substances MICROBIOPHARM JAPAN CO., LTD. (JP) 2005-11-03 — — US disclosed
EP-1548121-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES MERCIAN CORPORATION (JP) 2005-06-29 — — EP disclosed
EP-1541570-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCE MERCIAN CORPORATION (JP) 2005-06-15 — — EP disclosed
EP-1508570-A1 NOVEL PHYSIOLGICALLY ACTIVE SUBSTANCES MERCIAN CORPORATION (JP) 2005-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245514-A1 Novel physiologically active substances HIF1A, HIF1AN, VEGFA CYP2C19 1324/4885CYP1A2 1333/4885MEN1 2091/4885
US-20060241171-A1 Novel physiologically active substances HIF1A, HIF1AN, VEGFA CYP2C19 4132/4885CYP1A2 2803/4885MEN1 2851/4885
US-20060009439-A1 Novel physiologically active substances HIF1A, HIF1AN, VEGFA CYP2C19 4132/4885CYP1A2 2803/4885MEN1 2851/4885
US-20080275059-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES HIF1A, HIF1AN, VEGFA CYP2C19 4132/4885CYP1A2 2803/4885MEN1 2851/4885
US-20060235002-A1 Novel physiologically active substance HIF1AN, HIF1A, VEGFA CYP2C19 2189/4885CYP1A2 1561/4885MEN1 2966/4885
US-20080255146-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES HIF1A, HIF1AN, VEGFA CYP2C19 4132/4885CYP1A2 2803/4885MEN1 2851/4885
US-20160039834-A1 CARM1 INHIBITORS AND USES THEREOF CARM1, TIAM1, ADRM1 CYP2C19 1479/4885CYP1A2 731/4885MEN1 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.