Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488783 | 0.86 | MAOB (0.38) | CES2CES1MAPTMAOAMAOB | |
| SCHEMBL531137 | 0.86 | MAOB (0.38) | CES2CES1MAPTMAOAMAOB | |
| SCHEMBL6669859 | 0.78 | RAB9A (0.40) | MAPTMAOAMAOBSMN1; SMN2L3MBTL1 | |
| SCHEMBL2050414 | 0.77 | MAPT (0.39) | MAPTL3MBTL1MAPK1LMNAHTT | |
| SCHEMBL2050412 | 0.77 | MAPT (0.39) | MAPTL3MBTL1MAPK1LMNAHTT | |
| SCHEMBL28545178 | 0.74 | NPC1 (0.44) | MAPTSMN1; SMN2L3MBTL1MAPK1LMNA | |
| SCHEMBL3300226 | 0.71 | MAOB (0.38) | MAPTMAOAMAOBL3MBTL1MAPK1 | |
| SCHEMBL213003 | 0.71 | MAOB (0.38) | MAPTMAOAMAOBL3MBTL1MAPK1 | |
| SCHEMBL1269399 | 0.71 | MAPT (0.32) | MAPTL3MBTL1MAPK1LMNAHTT | |
| SCHEMBL213002 | 0.71 | MAOB (0.38) | MAPTMAOAMAOBL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028639-A1 | ROOM TEMPERATURE VULCANIZABLE POLYMERS | HONEYWELL INTERNATIONAL, INC. (US) | 2011-02-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028639-A1 | ROOM TEMPERATURE VULCANIZABLE POLYMERS | TET3, KDM3A, TET1 | CES2 3821/4885CES1 3924/4885MAPT 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.