Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488783 | 0.81 | MAOB (0.38) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL531137 | 0.81 | MAOB (0.38) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL1268952 | 0.78 | CES2 (0.37) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL1269399 | 0.77 | MAPT (0.32) | MAPTLMNAMAPK1L3MBTL1HTT | |
| SCHEMBL28759575 | 0.75 | MAPT (0.46) | RAB9AMAPTLMNAMAPK1L3MBTL1 | |
| SCHEMBL1078358 | 0.72 | ALDH1A1 (0.35) | TDP1 | |
| SCHEMBL29364929 | 0.70 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL29518667 | 0.70 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL1077251 | 0.70 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL1079335 | 0.69 | ALDH1A1 (0.32) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534588-A | STORAGE STABLE IN ONE-PACKAGE | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | claimed |
| EP-1238005-B1 | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS WITH IMPROVED ADHESION TO ACRYLIC | ALLIED SIGNAL INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6562931-B1 | A room temperature vulcanizable silicone rubber composition comprising; hydroxyl endblocked polyorganosiloxane; at least one phenyl-substituted, tris-functional ketoximinio silane; and an adhesion promoter consisting essentially one or more | ALLIEDSIGNAL INC. | 2003-05-13 | — | — | US | disclosed |
| EP-1238005-A1 | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS WITH IMPROVED ADHESION TO ACRYLIC | AlliedSignal Inc. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001032766-A1 | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS WITH IMPROVED ADHESION TO ACRYLIC | ALLIEDSIGNAL INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| US-5534588-A | STORAGE STABLE IN ONE-PACKAGE | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | disclosed |