Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18751732 | 1.00 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL17928352 | 0.91 | — | — | |
| SCHEMBL18751741 | 0.91 | — | — | |
| SCHEMBL18995798 | 0.91 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL24974550 | 0.90 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL12081887 | 0.90 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL21224008 | 0.90 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL22444953 | 0.90 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL589886 | 0.90 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL9917631 | 0.90 | HPGD (0.40) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120244172-A1 | Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents | SANOFI (FR) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244172-A1 | Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents | GABRA4, GABRA1, GABRA2 | HPGD 546/4885HTT 2504/4885SMN1; SMN2 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.