Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302371 | 0.90 | MAPT (0.59) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20619402 | 0.86 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27551570 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29608427 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL35884 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29363142 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3886256 | 0.83 | MEN1 (0.66) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL11124631 | 0.83 | MEN1 (0.66) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| Lithium SCHEMBL3886262 | 0.83 | MEN1 (0.66) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3886754 | 0.83 | MEN1 (0.66) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245213-A1 | HUMAN TYPE I TASTE RECEPTOR SUBUNIT 3 MODULATORS AND METHODS OF USING SAME | MOUNT SINAI SCHOOL OF MEDICINE | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245213-A1 | HUMAN TYPE I TASTE RECEPTOR SUBUNIT 3 MODULATORS AND METHODS OF USING SAME | TAS1R3, TAS2R3, TAS1R1 | MEN1 602/4885KMT2A 4619/4885ALDH1A1 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.