Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 6/20 | 0.53 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472269 | 0.87 | NUDT1 (0.44) | NUDT1CRHR1KCNH2JAK1L3MBTL1 | |
| SCHEMBL218367 | 0.85 | NUDT1 (0.51) | NUDT1JAK1L3MBTL1TLR8TLR7 | |
| SCHEMBL9885084 | 0.85 | NUDT1 (0.51) | NUDT1JAK1L3MBTL1TLR8TLR7 | |
| SCHEMBL250475 | 0.85 | NUDT1 (0.51) | NUDT1JAK1L3MBTL1TLR8TLR7 | |
| SCHEMBL217587 | 0.81 | BCL6 (0.47) | NUDT1CRHR1KCNH2JAK1L3MBTL1 | |
| SCHEMBL218483 | 0.81 | BCL6 (0.47) | NUDT1CRHR1 | |
| SCHEMBL9885018 | 0.81 | NUDT1 (0.55) | NUDT1L3MBTL1TLR8 | |
| SCHEMBL9884961 | 0.81 | NUDT1 (0.55) | NUDT1L3MBTL1TLR8 | |
| SCHEMBL20386651 | 0.81 | KCNH2 (0.59) | NUDT1KCNH2TLR8TLR7 | |
| SCHEMBL23472430 | 0.79 | TLR8 (0.57) | NUDT1KCNH2TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341145-A | Chemical compound | 博拉公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20120245169-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE LLC | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245169-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, PIK3CG, PIK3CB | NUDT1 791/4885CRHR1 4755/4885KCNH2 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.