SCHEMBL12695232

SCHEMBL12695232

CCCCC1COC(c2ccc(Br)cc2)OC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.43
CYP2D6 P10635 3/20 0.43
CYP2C19 P33261 3/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP2C9 P11712 1/20 0.43
KDM1A O60341 5/20 0.34
RCOR1 Q9UKL0 3/20 0.34
CYP1A2 P05177 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
MDM2 Q00987 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
KCNH2 Q12809 2/20 0.31
MAOB P27338 2/20 0.31
KDM1B Q8NB78 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746390 0.95 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL4863846 0.94 ALDH1A1 (0.41) CYP3A4CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL8746409 0.94 ALDH1A1 (0.41) CYP3A4CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL8746417 0.94 ALDH1A1 (0.41) CYP3A4CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL8916690 0.94 ALDH1A1 (0.41) CYP3A4CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL17355533 0.92 CYP3A4 (0.37) CYP3A4CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL10800140 0.84 GRM2 (0.39) CYP3A4CYP2C19TSHRALDH1A1CYP2C9
SCHEMBL8997203 0.84 GRM2 (0.38) KDM1ARCOR1CYP1A2SLC6A2SLC6A4
SCHEMBL8997302 0.84 MAPK1 (0.41) KDM1ARCOR1CYP1A2SLC6A3
SCHEMBL14224776 0.83 MEN1 (0.43) CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835739-B Disubstituted phenylethynyl fluorine boron pyrrole fluorescent dichromatic liquid crystal compound and application thereof 大连理工大学 2023-11-10 CN disclosed
CN-114835739-A Disubstituted phenylethynyl BODIPY fluorescent dichroic liquid crystal compound and application thereof 大连理工大学 2022-08-02 CN disclosed
US-20120241326-A1 METHOD OF PREPARING CONJUGATED POLYMER FUJIFILM CORPORATION (JP) 2012-09-27 US disclosed
US-20120241326-A1 METHOD OF PREPARING CONJUGATED POLYMER FUJIFILM CORPORATION (JP) 2012-09-27 US disclosed