SCHEMBL1269558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1269679	0.92	PTGDR2 (0.41)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL1268625	0.90	ALDH1A1 (0.39)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL1269368	0.89	PTGDR (0.39)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL1269875	0.86	PTGDR (0.39)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL1269486	0.86	ALDH1A1 (0.44)	PTGDR2ALDH1A1MEN1LMNAKMT2A
	SCHEMBL1270163	0.85	ALDH1A1 (0.41)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL1269799	0.85	PTGDR2 (0.40)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL1269276	0.85	MAPT (0.41)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL12900221	0.84	ALDH1A1 (0.41)	PTGDR2PTGDRALDH1A1MEN1LMNA
	SCHEMBL13452398	0.84	L3MBTL1 (0.38)	PTGDR2PTGDRALDH1A1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.