Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269679 | 0.92 | PTGDR2 (0.41) | L3MBTL1ALDH1A1GLAGAALMNA | |
| SCHEMBL1269489 | 0.89 | GAA (0.43) | L3MBTL1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL1269558 | 0.84 | PTGDR2 (0.42) | L3MBTL1ALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL1269670 | 0.84 | KMT2A (0.42) | ALDH1A1GLAGAALMNAHSD17B10 | |
| SCHEMBL1268625 | 0.81 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1GLAGAALMNA | |
| SCHEMBL1268669 | 0.81 | GAA (0.45) | ALDH1A1GLAGAALMNASMN1; SMN2 | |
| SCHEMBL1269715 | 0.79 | MEN1 (0.43) | ALDH1A1GAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL1269706 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAALMNASMN1; SMN2MEN1 | |
| SCHEMBL1269539 | 0.78 | KMT2A (0.43) | ALDH1A1GAALMNASMN1; SMN2MEN1 | |
| SCHEMBL12900218 | 0.77 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1GLAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786782-B1 | BISARYL-SULFONAMIDES | AMGEN INC (US) | 2010-03-31 | — | — | EP | disclosed |