SCHEMBL1269641

SCHEMBL1269641

C=Cc1ccccc1C(C)C[SiH](OC)OC

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1265798 0.75 TSHR (0.53) ALDH1A1TSHR
SCHEMBL11515634 0.75 TSHR (0.53) ALDH1A1TSHR
SCHEMBL2871086 0.74 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL28472908 0.74 TSHR (0.38) ALDH1A1CYP3A4TSHR
SCHEMBL11811176 0.73 TSHR (0.37) ALDH1A1TSHR
SCHEMBL2543708 0.72 TSHR (0.31) TSHR
SCHEMBL16536528 0.72 ALDH1A1 (0.31) ALDH1A1MEN1CYP3A4KMT2A
SCHEMBL7867358 0.72 ALDH1A1 (0.39) ALDH1A1MEN1CYP3A4KMT2ATSHR
SCHEMBL6281648 0.71 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL16537133 0.71 ALDH1A1 (0.30) ALDH1A1MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130037098-A1 INFRARED REFLECTIVE LAMINATE TECHNO POLYMER CO., LTD (JP) 2013-02-14 US disclosed
US-8339700-B2 Infrared reflective laminate TECHNO POLYMER CO., LTD (JP) 2012-12-25 US disclosed
US-20110284071-A1 MULTILAYER BODY Techno- Polymer Co., Ltd. (JP) 2011-11-24 US disclosed
US-20110061720-A1 LAMINATE TECHNO POLYMER CO., LTD. (JP) 2011-03-17 US disclosed
US-20110043901-A1 INFRARED REFLECTIVE LAMINATE TECHNO POLYMER CO., LTD. (JP) 2011-02-24 US disclosed
EP-2279863-A1 LAMINATE Techno Polymer Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20100189975-A1 LAYERED PRODUCT TECHNO POLYMER CO., LTD. (JP) 2010-07-29 US disclosed
EP-2204281-A1 INFRARED REFLECTIVE LAMINATE Techno Polymer Co., Ltd. (JP) 2010-07-07 EP disclosed
EP-2172337-A1 LAYERED PRODUCT Techno Polymer Co., Ltd. (JP) 2010-04-07 EP disclosed
US-5605962-A BLEND OF RUBBER REINFORCED RESIN WITH PHENOLIC RESIN AND ORGANOPHOSPHORUS COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-02-25 US disclosed
EP-0578873-B1 Flame-retardant resin composition DSM NV (NL) 1995-12-06 EP disclosed
EP-0612806-A1 Flame retarding resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-08-31 EP disclosed
EP-0578873-A1 Flame-retardant resin composition DSM N.V. (NL) 1994-01-19 EP disclosed