SCHEMBL7867358

SCHEMBL7867358

C=Cc1ccccc1C(C)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
CYP3A4 P08684 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP2C19 P33261 3/20 0.32
CYP2C9 P11712 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ACHE P22303 1/20 0.32
LMNA P02545 2/20 0.31
BLM P54132 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
THRB P10828 1/20 0.31
TFEB P19484 1/20 0.31
NFE2L2 Q16236 1/20 0.31
ALOX15 P16050 2/20 0.30
TSHR P16473 2/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2937719 0.82 ALDH1A1 (0.40) ALDH1A1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL14237001 0.82 LMNA (0.48) ALDH1A1MEN1KMT2ACYP2C19CYP2C9
SCHEMBL2357299 0.79 POLB (0.40) ALDH1A1KMT2ACYP2C19CYP2C9LMNA
SCHEMBL28767595 0.79 L3MBTL1 (0.36) ALDH1A1MEN1KMT2ACYP2C9LMNA
SCHEMBL6281523 0.79 ALDH1A1 (0.44) ALDH1A1CYP3A4MEN1KMT2ACA1
SCHEMBL29717597 0.79 GABRA1 (0.44) ALDH1A1CYP3A4KMT2ACYP2C19CYP2C9
SCHEMBL29364896 0.79 ALDH1A1 (0.44) ALDH1A1CYP3A4MEN1KMT2ACA1
SCHEMBL56243 0.79 GABRA1 (0.44) ALDH1A1CYP3A4KMT2ACYP2C19CYP2C9
SCHEMBL50011 0.79 ALDH1A1 (0.44) ALDH1A1CYP3A4MEN1KMT2ACA1
SCHEMBL5526822 0.78 GABRA1 (0.40) ALDH1A1CYP3A4CYP2C19CYP2C9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6299785-B1 Electrode formation process JSR CORPORATION (JP) 2001-10-09 US disclosed
US-4133799-A Benzofuranylphenol stabilizers THE B. F. GOODRICH COMPANY (US) 1979-01-09 US disclosed
US-4054551-A Benzofuranylphenol stabilizers THE B. F. GOODRICH COMPANY (US) 1977-10-18 US disclosed
US-3940364-A Naphthofuranylnaphthol stabilizers THE B. F. GOODRICH COMPANY (US) 1976-02-24 US disclosed