SCHEMBL2543708

SCHEMBL2543708

CO[SiH](CC(C)c1ccccc1CCl)OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3337272 0.84 TSHR (0.33) TSHR
SCHEMBL2100576 0.81 TSHR (0.33) TSHR
SCHEMBL1197512 0.81
SCHEMBL6036856 0.73 TSHR (0.31) TSHR
SCHEMBL11832647 0.73 NPBWR1 (0.32) TSHR
SCHEMBL1269641 0.72 ALDH1A1 (0.32) TSHR
SCHEMBL11846937 0.72 SLC6A2 (0.31) TSHR
SCHEMBL893214 0.72 GABRA1 (0.44) TSHR
SCHEMBL11837311 0.71 SLC6A2 (0.32) TSHR
SCHEMBL7716653 0.71 KCNA5 (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
US-20220162391-A1 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2022-05-26 US disclosed
US-20220016624-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X GENOMICS, INC. 2022-01-20 US disclosed
EP-3931639-A1 FUNCTIONAL HYDROGEN SILSESQUIOXANE RESINS AND THE USE THEREOF Pibond Oy (FI) 2022-01-05 EP disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
US-8501326-B2 Wax replacement specialty formulated corrugating adhesive HENKEL CORPORATION (US) 2013-08-06 US disclosed
US-20110259945-A1 WAX REPLACEMENT SPECIALTY FORMULATED CORRUGATING ADHESIVE HENKEL AG & CO. KGAA (DE) 2011-10-27 US disclosed
WO-2010080973-A2 WAX REPLACEMENT SPECIALTY FORMULATED CORRUGATING ADHESIVE HENKEL CORPORATION (US) 2010-07-15 WO disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
WO-2010054134-A1 WATERBORNE ADHESIVE HENKEL CORPORATION (US) 2010-05-14 WO disclosed
US-20100119741-A1 Waterborne Adhesive HENKEL CORPORATION 2010-05-13 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 TSHR 2847/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 TSHR 2847/4885
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 TSHR 3190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.