SCHEMBL12697331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12697442	0.88	SMN1; SMN2 (0.49)	ALDH1A1SMN1; SMN2LMNAKDM4EGAA
	SCHEMBL12477397	0.81	MAPT (0.61)	LMNAGAAMAPK1MAPTCNR1
	SCHEMBL12477063	0.76	MAPT (0.42)	L3MBTL1ALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL12476252	0.75	CA2 (0.38)	LMNAMAPK1HTT
	SCHEMBL14554519	0.74	MAPT (0.62)	LMNAHPGDKDM4EMAPK1MAPT
	SCHEMBL15116254	0.74	L3MBTL1 (0.61)	L3MBTL1ALDH1A1SMN1; SMN2LMNANPC1
	SCHEMBL12697384	0.74	PLAUR (0.53)	ALDH1A1LMNAHPGDKDM4EHSD17B10
	SCHEMBL12697404	0.73	CYP2A13 (0.52)	L3MBTL1ALDH1A1LMNANPC1HPGD
	SCHEMBL855566	0.73	TSHR (0.47)	L3MBTL1ALDH1A1SMN1; SMN2LMNANPC1
	SCHEMBL854130	0.72	L3MBTL1 (0.66)	L3MBTL1ALDH1A1KDM4EGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.