SCHEMBL126986

SCHEMBL126986

CCNS(=O)(=O)c1ccccc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.53
ALDH1A1 P00352 5/20 0.50
CA12 O43570 3/20 0.47
CA9 Q16790 3/20 0.47
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
BRD4 O60885 1/20 0.46
BRD2 P25440 1/20 0.46
BRD3 Q15059 1/20 0.46
RXFP1 Q9HBX9 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
EDNRA P25101 1/20 0.45
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
RAPGEF4 Q8WZA2 1/20 0.44
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30194714 1.00 PKM (0.53) PKMALDH1A1CA12CA9TP53
SCHEMBL27637625 0.88 ALDH1A1 (0.72) ALDH1A1CA12CA9L3MBTL1MEN1
SCHEMBL32664495 0.85 CA12 (0.61) PKMALDH1A1CA12CA9TP53
SCHEMBL634315 0.85 CA12 (0.61) PKMALDH1A1CA12CA9TP53
SCHEMBL9228164 0.85 ALDH1A1 (0.50) PKMALDH1A1CA12CA9BRD4
SCHEMBL16825009 0.82 PKM (0.51) PKMALDH1A1CA9TP53TDP1
SCHEMBL7200209 0.82 PKM (0.51) PKMALDH1A1CA12CA9TP53
SCHEMBL31391062 0.82 CA12 (0.63) PKMALDH1A1CA12CA9TP53
SCHEMBL1685390 0.82 ALDH1A1 (0.45) ALDH1A1CA12CA9BRD4BRD2
SCHEMBL635553 0.82 CA12 (0.63) PKMALDH1A1CA12CA9TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2023 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041654-A1 METHOD FOR PREVENTING OR TREATING INFLAMMATORY SKIN DISEASE GONGWIN BIOPHARM CO., LTD (TW) 2026-02-12 US claimed
US-12409158-B2 Combination therapy for treating cancer GONGWIN BIOPHARM CO., LTD (TW) 2025-09-09 US claimed
US-12390971-B2 Process and system for blending a plasticizer with a polysaccharide ester polymer CELANESE INTERNATIONAL CORPORATION (US) 2025-08-19 US claimed
US-20250244182-A1 HEAT-SENSITIVE MATERIAL FOR AN OVERHEATING DETECTION ELEMENT, AND ASSOCIATED DETECTION ELEMENT, ELECTRICAL EQUIPMENT AND ELECTRICAL ENCLOSURE SCHNEIDER ELECTRIC INDUSTRIES SAS (FR) 2025-07-31 US claimed
EP-4574144-A1 METHOD FOR TREATING PERIPHERAL NERVE SHEATH TUMOR Gongwin Biopharm Co., Ltd. (TW) 2025-06-25 EP claimed
CN-119894971-A Compositions containing cellulose ester polymers and enhanced melt strength agents 国际人造丝公司 2025-04-25 CN claimed
CN-119677507-A Combination therapy for the treatment of cancer 共信医药科技股份有限公司 2025-03-21 CN claimed
US-20250079447-A1 NEGATIVE ELECTRODE ACTIVE MATERIAL AND NEGATIVE ELECTRODE SHIN-ETSU CHEMICAL CO., LTD (JP) 2025-03-06 US claimed
EP-4465384-A1 NEGATIVE ELECTRODE ACTIVE MATERIAL AND NEGATIVE ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-11-20 EP claimed
CN-118617706-A High-strength polyethylene water supply pipe and preparation method thereof 大连天薇管业有限公司 2024-09-10 CN claimed
US-4297260-A Erasable writing medium composition LIQUID PAPER CORPORATION (US) 1981-10-27 US claimed
US-4240832-A CALCIUM HYDROXIDE WITH CONDENSATE OF A SALICYLATE ESTER AND AN ALDEHYDE SYBRON CORPORATION (US) 1980-12-23 US claimed
US-4222923-A Adhesive composition and method of use RHODES JOHN 1980-09-16 US claimed
US-4141869-A COPOLYAMIDE, HYDROPHOBIC SILICONE PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-02-27 US claimed
US-4093492-A HEAT SEALING PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-06-06 US claimed
US-4060262-A Record material THE STANDARD REGISTER COMPANY (US) 1977-11-29 US claimed
US-4030957-A HEAT SEALING PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-06-21 US claimed
US-4014847-A SULFONATED ADDITION POLYMERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-03-29 US claimed
US-3950297-A HEAT-SEALING AGENTS PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-04-13 US claimed
US-3948844-A HEAT SEALANTS PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-04-06 US claimed