SCHEMBL1685390

SCHEMBL1685390

CCNS(=O)(=O)c1cccc(C)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
CA12 O43570 4/20 0.43
CA9 Q16790 4/20 0.43
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
TRPA1 O75762 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
BRD4 O60885 1/20 0.39
BRD2 P25440 1/20 0.39
BRD3 Q15059 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GLA P06280 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599010 0.86 ALDH1A1 (0.43) ALDH1A1CA12CA9GAAMAPT
SCHEMBL5178084 0.84 CA12 (0.57) ALDH1A1CA12CA9GAAMAPT
SCHEMBL9228164 0.82 ALDH1A1 (0.50) ALDH1A1CA12CA9KDM4EHPGD
SCHEMBL10597168 0.82 ALDH1A1 (0.50) ALDH1A1CA12CA9GAAMAPT
SCHEMBL30194714 0.82 PKM (0.53) ALDH1A1CA12CA9MAPTALOX5AP
SCHEMBL126986 0.82 PKM (0.53) ALDH1A1CA12CA9MAPTALOX5AP
SCHEMBL9853187 0.81 KDM4E (0.50) ALDH1A1CA12CA9GAAMAPT
SCHEMBL9065942 0.80 ALDH1A1 (0.49) ALDH1A1CA12CA9GAAMAPT
SCHEMBL15741869 0.79 ALDH1A1 (0.46) ALDH1A1CA12CA9GAAMAPT
SCHEMBL3290138 0.79 ALDH1A1 (0.46) ALDH1A1CA12CA9GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3802695-B1 STRETCHABLE SOLID-STATE ELECTROACTIVE POLYMER ACTUATORS BIOASTRA TECH INC (CA) 2023-07-05 EP claimed
EP-3538070-B1 PHARMACEUTICAL COMPOSITION OF BENZENESULFONAMIDE DERIVATIVES FOR TREATMENT OF ADENOID CYSTIC CARCINOMA GONGWIN BIOPHARM CO LTD TAIWAN (TW) 2023-03-29 EP claimed
EP-3709962-B1 ANHYDROUS COMPOSITION COSMETICALLY ACCEPTABLE FOR USE AS NAIL POLISH INT LACQUERS (LU) 2022-01-26 EP claimed
EP-3625290-B1 MULTI-LAYER ANTI-FOG COMPOSITIONS AND PROCESSES FOR MAKING SAME CELANESE INT CORP (US) 2021-12-22 EP claimed
EP-3468547-B1 NOVEL BENZENESULFONAMIDE COMPOSITIONS FOR TREATMENT OF MALIGNANT PLEURAL EFFUSIONS GONGWIN BIOPHARM CO LTD TAIWAN (TW) 2021-10-06 EP claimed
EP-2552486-B1 TRANSDERMAL DELIVERY PATCH PHOSPHAGENICS LTD (AU) 2020-08-12 EP claimed
EP-3212703-B1 POLYMERIC PLASTICIZER COMPOSITIONS RESINATE MAT GROUP INC (US) 2019-05-01 EP claimed
EP-2483640-B1 THERMAL INK JET INK COMPOSITION VIDEOJET TECHNOLOGIES INC (US) 2018-05-09 EP claimed
EP-2606094-B1 SALT RESISTANT POLYAMIDE COMPOSITIONS DU PONT (US) 2017-02-01 EP claimed
EP-1943291-B1 HYDROLYSIS RESISTANT POLYAMIDE COMPOSITIONS, AND ARTICLES FORMED THEREFROM DU PONT (US) 2013-12-11 EP claimed
EP-1805442-B1 HYDROLYSIS RESISTANT POLYAMIDE COMPOSITIONS AND ARTICLES FORMED THEREFROM DU PONT (US) 2011-04-20 EP claimed
EP-1389101-B1 TOLUENE SULFONAMIDE-CONTAINING ANTI-TUMOR COMPOSITION AND METHOD OF USE THEREOF PTS INTERNATIONAL INC (US) 2008-12-03 EP claimed
EP-1805264-B1 MARINE UMBILICAL COMPRISING HYDROLYSIS RESISTANT POLYAMIDES DU PONT (US) 2008-10-08 EP claimed
EP-0801663-B1 CURABLE SEALER AND/OR ADHESIVE COMPOSITION, METHOD FOR COATING SAME AND COATED SUBSTRATES MINNESOTA MINING & MFG (US) 1999-08-18 EP claimed
EP-0497514-B1 Electrically conductive blends of intrinsically conductive polymers and thermoplastic polymers and a process for their preparation AMERICHEM INC (US) 1997-03-19 EP claimed
EP-0233623-B1 PHOTOPOLYMERIZABLE FILMS CONTAINING PLASTICIZER SILICA COMBINATIONS HERCULES INCORPORATED (US) 1993-07-21 EP claimed
EP-0170000-B1 NAIL POLISH COMPOSITIONS AND MEANS FOR APPLYING SAME CHESEBROUGH-POND'S INC. (US) 1991-07-24 EP claimed
EP-0154679-B1 NAIL COATING COMPOSITIONS AND PROCESS FOR PREPARING SAME CHESEBROUGH-POND'S INC. (US) 1990-08-29 EP claimed
US-8487016-B2 Dental impression material containing rheological modifiers and process of production 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-16 US disclosed
EP-0430705-A1 Dental cement composition BTG INTERNATIONAL LIMITED (GB) 1991-06-05 EP disclosed