Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12699603 | 0.91 | KDM4E (0.46) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL13309515 | 0.91 | KDM4E (0.46) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL12699732 | 0.91 | KDM4E (0.46) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL13309269 | 0.90 | KDM4E (0.43) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL12019897 | 0.90 | KDM4E (0.46) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL20654708 | 0.89 | KDM4E (0.41) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL24356562 | 0.89 | KDM4E (0.41) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL25972718 | 0.89 | ALDH1A1 (0.38) | KDM4EATML3MBTL1F2F10 | |
| SCHEMBL12699606 | 0.89 | KDM4E (0.43) | MCL1ACMSDKDM4EATML3MBTL1 | |
| SCHEMBL20826214 | 0.88 | MCL1 (0.41) | MCL1ACMSDNTSR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627732-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-9653687-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9653687-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| EP-2787053-A1 | Polymeric materials | Merck Patent GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130228767-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK | 2013-09-05 | — | — | US | disclosed |
| US-20130228767-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK | 2013-09-05 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130200357-A1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-20130200357-A1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| WO-2012048900-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. . (DE) | 2012-04-19 | — | — | WO | disclosed |
| EP-2102309-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| WO-2008086851-A1 | CARBAZOLE DERIVATIVES FOR ORGANC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, CACNA2D1, CYCS | MCL1 1429/4885ACMSD 1063/4885KDM4E 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.