Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500801 | 0.97 | L3MBTL1 (0.50) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL21709230 | 0.97 | KDM4E (0.46) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19500800 | 0.95 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19036992 | 0.95 | KDM4E (0.49) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19500798 | 0.95 | KDM4E (0.49) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19500797 | 0.95 | L3MBTL1 (0.53) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19500802 | 0.94 | ATM (0.47) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19500799 | 0.94 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19131225 | 0.93 | ATM (0.46) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL19500787 | 0.93 | KDM4E (0.46) | KDM4EATML3MBTL1HDAC4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627730-B1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |
| EP-2627732-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-9653687-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9653687-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| EP-2787053-A1 | Polymeric materials | Merck Patent GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130228767-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK | 2013-09-05 | — | — | US | disclosed |
| US-20130228767-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK | 2013-09-05 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130200357-A1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-20130200357-A1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| WO-2012048900-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. . (DE) | 2012-04-19 | — | — | WO | disclosed |
| EP-2102309-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| WO-2008086851-A1 | CARBAZOLE DERIVATIVES FOR ORGANC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, CACNA2D1, CYCS | KDM4E 3257/4885ATM 3616/4885L3MBTL1 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.