Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.63 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12698839 | 0.87 | NR1H4 (0.64) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL15676754 | 0.85 | NPC1 (0.61) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL12698754 | 0.85 | RAB9A (0.64) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL17664548 | 0.84 | NPC1 (0.59) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL1696476 | 0.83 | NPC1 (0.58) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL18132528 | 0.82 | ROCK2 (0.63) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL10685426 | 0.82 | NR1H4 (0.73) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL1690509 | 0.82 | NPC1 (0.57) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL903576 | 0.80 | MEN1 (0.75) | TP53MEN1KMT2AFFAR1GLA | |
| SCHEMBL12698773 | 0.80 | POLB (0.60) | TP53MEN1KMT2AFFAR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012129562-A2 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-09-27 | — | — | WO | disclosed |