Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGR | P09769 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748863 | 0.87 | MEN1 (0.42) | ABL1SRCCYP1A2RIPK2EGFR | |
| SCHEMBL7515835 | 0.86 | CLK4 (0.42) | CNR1CNR2ALPLABL1SRC | |
| SCHEMBL7826933 | 0.80 | IKBKB (0.46) | CNR1CNR2ALPLIKBKBABL1 | |
| SCHEMBL6055066 | 0.78 | KDM4E (0.50) | ABL1SRCEGFRHCKKDR | |
| SCHEMBL1270137 | 0.77 | ABL1 (0.57) | CNR1CNR2ALPLIKBKBMAP3K14 | |
| SCHEMBL3715031 | 0.75 | SRC (0.57) | ALPLIKBKBMAP3K14ABL1SRC | |
| SCHEMBL13020474 | 0.74 | IKBKB (0.44) | ALPLIKBKBMAP3K14ABL1SRC | |
| SCHEMBL8402143 | 0.72 | BTK (0.55) | BTKTNK2 | |
| SCHEMBL5088174 | 0.69 | PIK3CD (0.60) | ABL1SRCCYP1A2DAPK3RIPK2 | |
| SCHEMBL14735752 | 0.69 | PRKACA (0.44) | CNR1ALPLABL1SRCCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482983-A4 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RES DEV CO (IL) | 2006-07-12 | — | — | EP | claimed |
| EP-1482983-A2 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-12-08 | — | — | EP | claimed |
| WO-2003065971-A2 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-08-14 | — | — | WO | claimed |
| EP-3303566-A2 | MATURATION OF MAMMALIAN HEPATOCYTES | Takara Bio Europe AB (SE) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016193441-A2 | MATURATION OF MAMMALIAN HEPATOCYTES | TAKARA BIO EUROPE AB (SE) | 2016-12-08 | — | — | WO | disclosed |
| WO-2011014239-A1 | ANTI-PROLIFERATIVE SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDINES DERIVATIVES (SPP) TO INHIBIT IMMUNE ACTIVATION, VIRUS REPLICATION AND TUMOR GROWTH | VIROSTATICS SRL (IT) | 2011-02-03 | — | — | WO | disclosed |