SCHEMBL1270146

SCHEMBL1270146

O=C1OC(O)C(CCl)=C1Cl

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mucochloric Acid SCHEMBL1010785 0.72
SCHEMBL16245792 0.68
SCHEMBL2143796 0.65 ALDH1A1 (1.00) ALDH1A1HIF1AHSD17B10
SCHEMBL4302916 0.64 ALDH1A1 (0.68) ALDH1A1HIF1AHSD17B10
SCHEMBL3908860 0.63 ALDH1A1 (0.71) ALDH1A1HIF1AHSD17B10
SCHEMBL20016461 0.61 APP (0.33) ALDH1A1HIF1AHSD17B10
SCHEMBL11832803 0.61 MAPT (0.34) ALDH1A1HIF1AHSD17B10
Mucochloric Acid SCHEMBL31295685 0.59 ALDH1A1 (0.42) ALDH1A1HIF1AHSD17B10
Mucochloric Acid SCHEMBL31295686 0.59 ALDH1A1 (0.42) ALDH1A1HIF1AHSD17B10
SCHEMBL11276380 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136987-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2025-05-01 US disclosed
EP-4491184-A2 CHANNEL MODULATORS Auckland Uniservices Limited (NZ) 2025-01-15 EP disclosed
EP-3183346-B1 CHANNEL MODULATORS AUCKLAND UNISERVICES LTD (NZ) 2024-10-23 EP disclosed
US-20230174980-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2023-06-08 US disclosed
US-11401516-B2 Channel modulators AUCKLAND UNISERVICES LIMITED (NZ) 2022-08-02 US disclosed
CN-114010788-A Channel modulators 奥克兰联合服务有限公司 2022-02-08 CN disclosed
US-20210115445-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2021-04-22 US disclosed
US-20200263175-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2020-08-20 US disclosed
US-20200239889-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2020-07-30 US disclosed
US-10465188-B2 Channel modulators AUCKLAND UNISERVICES LIMITED (NZ) 2019-11-05 US disclosed
WO-2009097077-A2 WOUND HEALING COMPOSITIONS AND TREATMENTS CODA THERAPEUTICS, INC. (US) 2009-08-06 WO disclosed
WO-2009085274-A2 USE OF ANTI-CONNEXIN POLYNUCLEOTIDES AND PEPTIDES FOR THE TREATMENT OFABNORMAL OR EXCESSIVE SCARS CODA THERAPEUTICS, INC. (US) 2009-07-09 WO disclosed
WO-2009085268-A2 USE OF ANTI-CONNEXIN PEPTIDES, ALONE OR IN COMBINATION WITH ANTI-CONNEXIN POLYNUCLEOTIDES, FOR THE TREATMENT OF SURGICAL ADHESIONS CODA THERAPEUTICS, INC. (US) 2009-07-09 WO disclosed
WO-2009085275-A2 USE OF ANTI-CONNEXIN POLYPEPTIDE AGENT IN COMBINATION WITH ANTI-CONNEXIN POLYNUCLEOTIDE AGENT FOR THE TREATMENT OF FIBROTIC CONDITIONS CODA THERAPEUTICS, INC. (US) 2009-07-09 WO disclosed
WO-2009085271-A2 USE OF ANTI-CONNEXIN PEPTIDES, ALONE OR IN COMBINATION WITH ANTI-CONNEXIN POLYNUCLEOTIDES, FOR THE TREATMENT OF ORTHOPEDIC CONDITIONS CODA THERAPEUTICS, INC. (US) 2009-07-09 WO disclosed
WO-2009085272-A2 IMPROVED MEDICAL DEVICES CODA THERAPEUTICS, INC. (US) 2009-07-09 WO disclosed
WO-2009075881-A2 IMPAIRED WOUND HEALING COMPOSITIONS AND TREATMENTS CODA THERAPEUTICS, INC. (US) 2009-06-18 WO disclosed
WO-2009075882-A2 IMPAIRED WOUND HEALING COMPOSITIONS AND TREATMENTS CODA THERAPEUTICS, INC. (US) 2009-06-18 WO disclosed
WO-2008060622-A9 IMPROVED METHODS AND COMPOSITIONS FOR WOUND HEALING CODA THERAPEUTICS INC (US) 2008-11-27 WO disclosed
WO-2008060622-A2 IMPROVED METHODS AND COMPOSITIONS FOR WOUND HEALING CODA THERAPEUTICS, INC. (US) 2008-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174980-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885
US-20200263175-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885
US-10465188-B2 Channel modulators GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885
US-11401516-B2 Channel modulators GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885
US-20200239889-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885
US-20250136987-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885
US-20210115445-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 ALDH1A1 3694/4885HIF1A 1117/4885HSD17B10 4389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.