Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703678 | 0.96 | CNR2 (0.32) | PDK2POLBHSD17B1HSD17B2 | |
| SCHEMBL12703324 | 0.95 | PDK2 (0.33) | PDK2HSD17B1HSD17B2 | |
| SCHEMBL12703208 | 0.91 | PGR (0.36) | PDK2POLBPGRHSD17B1HSD17B2 | |
| SCHEMBL12703694 | 0.90 | PGR (0.36) | PDK2POLBPGRHSD17B1HSD17B2 | |
| SCHEMBL12703361 | 0.90 | PDK2 (0.32) | PDK2HSD17B1HSD17B2 | |
| SCHEMBL12703406 | 0.89 | KCNK3 (0.32) | PDK2 | |
| SCHEMBL12703128 | 0.89 | POLB (0.32) | PDK2POLBACHE | |
| SCHEMBL12703169 | 0.88 | ALDH1A1 (0.31) | PDK2 | |
| SCHEMBL12703387 | 0.86 | PDK2 (0.32) | PDK2 | |
| SCHEMBL12703227 | 0.86 | HTR7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276723-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8766001-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8766001-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-04-21 | — | — | US | disclosed |
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | SLCO4C1, SLCO2A1, TOE1 | PDK2 2449/4885POLB 1395/4885PGR 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.