SCHEMBL12705016

SCHEMBL12705016

O=C(OCC1CCCCC1)C(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
SLC1A3 P43003 4/20 0.43
SLC1A2 P43004 4/20 0.43
SLC1A1 P43005 4/20 0.43
PARP10 Q53GL7 3/20 0.38
PARP15 Q460N3 2/20 0.38
MGLL Q99685 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
CA9 Q16790 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12705025 1.00 LMNA (0.52) LMNASLC1A3SLC1A2SLC1A1PARP10
SCHEMBL12705020 1.00 LMNA (0.52) LMNASLC1A3SLC1A2SLC1A1PARP10
SCHEMBL12705015 0.98 LMNA (0.48) LMNASLC1A3SLC1A2SLC1A1PARP10
SCHEMBL12705014 0.94 LMNA (0.44) LMNASLC1A3SLC1A2SLC1A1PARP10
SCHEMBL12705009 0.89 SLC1A3 (0.38) LMNASLC1A3SLC1A2SLC1A1PARP10
SCHEMBL12705307 0.87 LMNA (0.53) LMNASLC1A3SLC1A2SLC1A1PARP10
SCHEMBL12705090 0.82 SLC1A3 (0.34) LMNASLC1A3SLC1A2SLC1A1
SCHEMBL12705087 0.82 SLC1A3 (0.34) LMNASLC1A3SLC1A2SLC1A1
SCHEMBL12705089 0.81 LMNA (0.35) LMNASLC1A3SLC1A2SLC1A1
SCHEMBL17281568 0.81 LMNA (0.46) LMNASLC1A3SLC1A2SLC1A1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110091808-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091808-A1 PHOTORESIST COMPOSITION ASIC1, ASIC3, SUN2 LMNA 3534/4885SLC1A3 319/4885SLC1A2 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.