Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | MC3R | P41968 | 8/20 | 0.48 |
| ▸ | MC5R | P33032 | 7/20 | 0.48 |
| ▸ | MC4R | P32245 | 7/20 | 0.48 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478156 | 0.88 | OPRM1 (0.61) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL12706706 | 0.88 | OPRM1 (0.61) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL13739916 | 0.88 | OPRM1 (0.61) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL12706637 | 0.84 | MEN1 (0.46) | MC3RMC5RMC4RMC1RHDAC3 | |
| SCHEMBL12706635 | 0.81 | DRD2 (0.49) | MC3RMC4RMC1RHDAC3HDAC4 | |
| SCHEMBL19831554 | 0.81 | OPRM1 (0.61) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL23318156 | 0.79 | OPRM1 (0.64) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL23317973 | 0.77 | OPRM1 (0.58) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL29664052 | 0.76 | MC3R (0.80) | OPRM1OPRD1MC3RMC5RMC4R | |
| SCHEMBL12971657 | 0.75 | TSLP (0.48) | OPRM1OPRD1MC3RMC5RMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919459-B2 | Cardiovascular disorders; antidiabetic agents; respiratory system disorders; antagonist of protein g receptor | PROMICS PTY LIMITED (AU) | 2011-04-05 | — | — | US | disclosed |
| US-7919459-B2 | Cardiovascular disorders; antidiabetic agents; respiratory system disorders; antagonist of protein g receptor | PROMICS PTY LIMITED (AU) | 2011-04-05 | — | — | US | disclosed |