SCHEMBL437296

SCHEMBL437296

C=Cc1cccc([Si](OCC)(OCC)OCC)c1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
TRPA1 O75762 1/20 0.32
PTGS2 P35354 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434674 1.00 TP53 (0.44) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL29434608 0.87 TP53 (0.42) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL5701495 0.87 TP53 (0.42) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL29434597 0.85 TP53 (0.43) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL23493464 0.85 TP53 (0.43) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL29434629 0.84 TP53 (0.40) TP53TDP1ALDH1A1TSHR
SCHEMBL23493421 0.84 TP53 (0.40) TP53TDP1ALDH1A1TSHR
SCHEMBL21829873 0.83 TP53 (0.39) TP53TDP1TSHR
SCHEMBL6906357 0.82
SCHEMBL574271 0.81 TP53 (0.33) TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
EP-4130050-B1 CONJUGATED DIENE POLYMER, METHOD FOR MANUFACTURING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND RUBBER COMPOSITION ASAHI CHEMICAL IND (JP) 2024-10-09 EP disclosed
EP-4424733-A1 BLOCK COPOLYMER, ASPHALT COMPOSITION, AND MODIFIED ASPHALT MIXTURE Asahi Kasei Kabushiki Kaisha (JP) 2024-09-04 EP disclosed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN disclosed
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 TP53 4532/4885TDP1 1360/4885ALDH1A1 2948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.