Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 12/20 | 0.40 |
| ▸ | NNMT | P40261 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419098 | 0.83 | MAP4K1 (0.43) | MAP4K1ABL1MAPK1NNMTAURKA | |
| SCHEMBL12708357 | 0.81 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL13578554 | 0.78 | EPHX2 (0.50) | MAPK1NNMT | |
| SCHEMBL12708366 | 0.77 | ALDH1A1 (0.39) | MAP4K1MAPK1 | |
| SCHEMBL1554212 | 0.71 | RAB9A (0.46) | MAP4K1MAPK1NNMT | |
| SCHEMBL12708318 | 0.70 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL13101606 | 0.70 | ABL1 (0.57) | MAP4K1ABL1MAPK1 | |
| SCHEMBL12832808 | 0.69 | EPHX2 (0.45) | MAPK1 | |
| SCHEMBL25920210 | 0.67 | L3MBTL1 (0.50) | MAP4K1ABL1MAPK1 | |
| SCHEMBL5256669 | 0.66 | RAB9A (0.57) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102199-B1 | ANTIBACTERIAL POLYCYCLIC UREA COMPOUNDS | ASTRAZENECA AB (SE) | 2011-04-27 | — | — | EP | disclosed |