Quinoline

Quinoline

SCHEMBL1270969

c1ccc2ncccc2c1.c1ccc2ncccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
NPC1 O15118 2/20 0.58
POLB P06746 1/20 0.58
RAB9A P51151 1/20 0.58
CYP3A4 P08684 3/20 0.56
MAPT P10636 5/20 0.54
HTT P42858 3/20 0.54
KDM4E B2RXH2 3/20 0.54
CASP1 P29466 2/20 0.54
TP53 P04637 2/20 0.54
HSP90AA1 P07900 2/20 0.54
TSHR P16473 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
MEN1 O00255 1/20 0.54
CASP7 P55210 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
NR4A2 P43354 1/20 0.54
HSP90AB1 P08238 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL32661377 1.00 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29349552 1.00 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL2774 1.00 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29822171 1.00 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL23202414 0.97 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL5422407 0.97 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL4955314 0.97 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL18062510 0.97 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL20969722 0.97 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL1935828 0.97 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290489-A Cobalt nitride metal complex and application thereof in synthesis of beta-hydroxy propionate 中化泉州石化有限公司 2024-07-05 CN claimed
CN-112266402-A Polypyridine ruthenium complex and preparation method and application thereof 深圳大学 2021-01-26 CN claimed
CN-105849959-B Polymer dielectric film, the membrane-electrode assembly including polymer dielectric film and the fuel cell including membrane-electrode assembly 株式会社LG化学 2019-11-19 CN claimed
CN-110418574-A FUNGICIDAL COMBINATIONS UPL LTD 2019-11-05 CN claimed
CN-110312726-A Compound based on boron group element and its purposes in electrolyte composition 斯塞法国公司 2019-10-08 CN claimed
CN-110195032-A Hyphomicrobium LXL-PQ-409 and its application 浙江工商大学 2019-09-03 CN claimed
CN-110139648-A Formulations, methods, kits and dosage forms for treating bacterial infections 莫迪福生物科学股份有限公司 2019-08-16 CN claimed
CN-105408320-B 3- (aryl or heteroaryl) methyl indol -2- ketone derivatives as cancer stem cell approach kinase inhibitor for treating cancer 北京强新生物科技有限公司 2019-08-13 CN claimed
CN-107474866-B A kind of preparation method of high-quality mesophase pitch 上海高强高模新材料科技有限公司 2019-08-06 CN claimed
CN-107108862-B Conjugated polymers containing ethynyl crosslinking groups, mixtures, compositions, organic electronic devices comprising the same, and uses thereof 广州华睿光电材料有限公司 2019-08-02 CN claimed
CN-1319950-C 3-substituted-4-pyrimidone derivatives MITSUBISHI PHARMA CORP (JP) 2007-06-06 CN claimed
CN-1308771-C Silver halide emulsion, silver halide color photosensitive material using the same and image forming method FUJI PHOTO FILM CO LTD (JP) 2007-04-04 CN claimed
CN-1454086-A High affinity small molecule C5A receptor modulators NEUROGEN CORP (US) 2003-11-05 CN claimed
EP-0585745-B1 Direct positive silver halide photographic material and method for forming high contrast positive image using the same DAINIPPON INK & CHEMICALS (JP) 1999-03-24 EP claimed
CN-1186795-A Method for preparing aromatic compounds ROHM & HAAS (US) 1998-07-08 CN claimed
US-5362621-A Compound containing pyridine and pyridinium nucleus, reductone developer DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-11-08 US claimed
EP-0585745-A2 Direct positive silver halide photographic material and method for forming high contrast positive image using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-09 EP claimed
US-4753722-A OXIDATION TO DISULFIDES MERICHEM COMPANY (US) 1988-06-28 US claimed
US-4254198-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1981-03-03 US claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed