Quinoline

Quinoline

SCHEMBL20969722

[Pd].c1ccc2ncccc2c1

nearest known ligand 0.94

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.94
NPC1 O15118 2/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
CYP3A4 P08684 3/20 0.54
MAPT P10636 4/20 0.52
HTT P42858 3/20 0.52
KDM4E B2RXH2 3/20 0.52
CASP1 P29466 2/20 0.52
TP53 P04637 2/20 0.52
HSP90AA1 P07900 2/20 0.52
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 1/20 0.52
CASP7 P55210 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
NR4A2 P43354 1/20 0.52
HSP90AB1 P08238 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27647789 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27885928 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL2774 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL1270969 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29349552 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL32661377 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29822171 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL23202414 0.94 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL506172 0.94 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL6381814 0.94 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462775-A Quinoline imine palladium complex, preparation method and application thereof 链行走新材料科技(广州)有限公司 2025-02-18 CN claimed
CN-119462774-A Quinoline formaldehyde palladium complex and preparation method and application thereof 链行走新材料科技(广州)有限公司 2025-02-18 CN claimed
CN-108226101-A Optochemical sensor 梅特勒-托莱多有限公司 2018-06-29 CN claimed
CN-119462774-A Quinoline formaldehyde palladium complex and preparation method and application thereof 链行走新材料科技(广州)有限公司 2025-02-18 CN disclosed
CN-118702741-A Palladium complex containing quinolinyl triazolopyrazine ligand and preparation method and application thereof 山西大学 2024-09-27 CN disclosed
CN-113198538-B Preparation method of super-strong fiber supported Schiff base palladium catalyst 江苏关山度新材料科技有限公司 2023-10-03 CN disclosed
CN-113198538-A Preparation method of superstrong fiber-loaded Schiff base palladium catalyst 江苏关山度新材料科技有限公司 2021-08-03 CN disclosed
EP-3481973-A1 SELECTIVE ELECTROCHEMICAL HYDROGENATION OF ALKYNES TO ALKENES Siemens Aktiengesellschaft (DE) 2019-05-15 EP disclosed
CN-106010510-B A kind of multifunctional rare-earth metal-organic framework material converted for light and preparation method thereof 武汉大学 2018-07-03 CN disclosed
CN-87105816-A The preparation method of triazolyl tetrahydrofuran (THF) and can be used for the new compound of described compound 1988-03-02 CN disclosed