SCHEMBL1271014

SCHEMBL1271014

O=C(O)CCCOc1ccc(Oc2ccccc2O)cc1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.68
FFAR1 O14842 6/20 0.57
PPARA Q07869 3/20 0.54
LTA4H P09960 2/20 0.51
SERPINE1 P05121 1/20 0.48
CYSLTR2 Q9NS75 1/20 0.48
CYSLTR1 Q9Y271 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1271028 0.92 FFAR4 (0.58) FFAR4FFAR1PPARALTA4H
SCHEMBL28157802 0.84 GAA (0.62) FFAR4PPARA
SCHEMBL11587499 0.84 FFAR4 (0.75) FFAR4FFAR1PPARALTA4H
SCHEMBL2349792 0.84 FFAR1 (0.58) FFAR4FFAR1
SCHEMBL1270505 0.83 ALOX15 (0.61) FFAR4FFAR1
SCHEMBL1271015 0.82 FFAR4 (0.60) FFAR4FFAR1PPARALTA4HCYSLTR2
SCHEMBL16335007 0.81 FFAR4 (1.00) FFAR4FFAR1PPARALTA4H
SCHEMBL3424970 0.80 FFAR1 (0.71) FFAR4FFAR1
SCHEMBL295889 0.80 PPARA (0.66) FFAR4FFAR1PPARALTA4H
SCHEMBL31448501 0.80 PPARA (0.65) FFAR4FFAR1PPARASERPINE1CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080015-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-07-14 US disclosed
US-20120178885-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-07-12 US disclosed
EP-2459637-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2012-06-06 EP disclosed
WO-2011014859-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-02-03 WO disclosed