SCHEMBL1271015

SCHEMBL1271015

O=C(O)CCCOc1ccccc1Oc1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.60
FFAR1 O14842 4/20 0.50
ESR1 P03372 2/20 0.50
LMNA P02545 1/20 0.50
PPARA Q07869 2/20 0.47
LTA4H P09960 2/20 0.46
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
CAMK2A Q9UQM7 1/20 0.46
CYSLTR2 Q9NS75 1/20 0.45
CYSLTR1 Q9Y271 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1271029 0.92 LMNA (0.59) FFAR4FFAR1ESR1LMNALTA4H
SCHEMBL1271016 0.85 CAMK2A (0.57) FFAR4FFAR1ESR1LMNALTA4H
SCHEMBL1270506 0.83 L3MBTL1 (0.57) FFAR1ESR1LMNALTA4HNR1H2
SCHEMBL9762157 0.82 LMNA (0.67) FFAR4FFAR1LMNALTA4HCAMK2A
SCHEMBL1271014 0.82 FFAR4 (0.68) FFAR4FFAR1PPARALTA4HCYSLTR2
SCHEMBL2349794 0.81 FFAR1 (0.58) FFAR4FFAR1ESR1LTA4HNR1H2
SCHEMBL1271045 0.80 ESR1 (0.59) FFAR4FFAR1ESR1PPARALTA4H
SCHEMBL10535442 0.79 LMNA (0.58) FFAR4FFAR1LMNALTA4H
SCHEMBL8148979 0.79 LMNA (0.61) FFAR4LMNAPPARACYSLTR2CYSLTR1
SCHEMBL8162827 0.79 LMNA (0.61) FFAR4LMNAPPARACYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080015-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-07-14 US disclosed
US-20120178885-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-07-12 US disclosed
EP-2459637-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2012-06-06 EP disclosed
WO-2011014859-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-02-03 WO disclosed