SCHEMBL2349792

SCHEMBL2349792

O=C(O)CCCc1ccc(Oc2ccccc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.58
HDAC3 O15379 1/20 0.57
MAPK1 P28482 1/20 0.57
ADRA1A P35348 1/20 0.57
HDAC4 P56524 1/20 0.57
SLC6A3 Q01959 1/20 0.57
HDAC1 Q13547 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC2 Q92769 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
HDAC9 Q9UKV0 1/20 0.57
HDAC5 Q9UQL6 1/20 0.57
CYP1A2 P05177 1/20 0.51
SRD5A2 P31213 1/20 0.51
FFAR4 Q5NUL3 4/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3424970 0.91 FFAR1 (0.71) FFAR1SRD5A2FFAR4
SCHEMBL27615885 0.84 FFAR1 (0.80) FFAR1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL1271014 0.84 FFAR4 (0.68) FFAR1FFAR4
SCHEMBL70972 0.82 FFAR1 (0.70) FFAR1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL2353782 0.81 SRD5A2 (0.59) SRD5A2MAPT
SCHEMBL2349797 0.80 FFAR1 (0.62) FFAR1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL1271028 0.79 FFAR4 (0.58) FFAR1FFAR4
SCHEMBL10276941 0.78 FFAR1 (0.75) FFAR1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL2349794 0.77 FFAR1 (0.58) FFAR1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL1666509 0.76 SLC1A5 (0.51) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476399-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-07-02 US disclosed
US-20130085238-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-04-04 US disclosed
US-8252887-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-08-28 US disclosed
EP-2349981-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2011-08-03 EP disclosed
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY (US) 2010-09-16 US disclosed
WO-2010042918-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES ECPAS, PTGIR, RXFP1 FFAR1 827/4885HDAC3 2887/4885MAPK1 2795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.